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Symptoms of hepatitis A can include: Fever, tiredness, loss of appetite, nausea and vomiting Severe stomach pains and diarrhea Jaundice (yellow skin or eyes, dark urine, clay-colored bowel movements) These symptoms usually appear 2-6 weeks after exposure and typically last less than 2 months, although some people can be ill for as long as 6 months

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These differences complicate the ability to assess smoking-induced microbiome alterations and associated disease mechanisms in humans [140, 141]

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